What is the primary function of Lymphotoxin?

What is the primary function of Lymphotoxin?

• A. Causes apoptosis in target cells
• B. Promotes immune cell proliferation
• C. Causes lysis of infected or cancerous cells
• D. Stimulates the production of antibodies

Answer: (C)

Lymphotoxin is a cytokine produced primarily by T cells, particularly cytotoxic T lymphocytes and natural killer (NK) cells. Its primary function is to induce lysis, or destruction, of infected or cancerous cells. This mechanism is crucial for the immune response, as lymphotoxin effectively eliminates cells that pose a threat to the body, such as those that are virally infected or malignantly transformed.

By triggering apoptosis in these compromised cells, lymphotoxin plays a vital role in controlling infections and preventing the spread of cancer. Its action helps to maintain homeostasis within the immune system, ensuring that only healthy cells remain while targeting those that exhibit abnormal behaviors. This process is essential for immune surveillance and the overall effectiveness of the body's defense mechanisms.